Updated July 28, 2022
Whether you call it neuter, spay, castrate or desex, the right time to get it done in dogs is a subject of much debate. This is because it varies from breed to breed. Recently, a study was published on the best age for neutering in Boxers.
While the paper isn’t perfect (more on that later), it does provide the first evidence for Boxers on choosing a time of desexing with the fewest health problems. The study compared dogs neutered at different ages for their rates of:
- hip dysplasia (HD), cruciate ligament injury (CCL) and elbow dysplasia (ED)
- lymphoma (LSA), mast cell tumour (MCT), haemangiosarcoma (HSA), osteosarcoma (OSA)
- urinary incontinence (UI)
All of these have been suspected to be linked with the age of neutering. Here’s what they found (only bold values are significant, my summary to follow):
HD | CCL | ED | At Least One | |
Male < 6 months | 0/30 (0) | 1/30 (3.33) | 0/30 (0) | 1/29 (3.45) |
Male 6 – 11 months | 0/60 (0) | 1/58 (1.72) | 0/60 (0) | 1/56 (1.79) |
Male 1 year | 0/39 (0) | 1/37 (2.7) | 0/39 (0) | 1/37 (2.7) |
Male 2 – 8 years | 0/64 (0) | 0/62 (0) | 0/65 (0) | 0/62 (0) |
Male Intact | 0/217 (0) | 4/219 (1.83) | 0/218 (0) | 4/214 (1.87) |
Female < 6 months | 0/48 (0) | 1/48 (2.08) | 0/50 (0) | 1/46 (2.17) |
Female 6 – 11 months | 0/70 (0) | 2/69 (2.9) | 0/70 (0) | 2/69 (2.9) |
Female 1 year | 0/29 (0) | 0/29 (0) | 0/29 (0) | 0/29 (0) |
Female 2 – 8 years | 0/60 (0) | 3/58 (5.17) | 0/60 (0) | 3/58 (5.17) |
Female Intact | 1/126 (0.79) | 3/129 (2.33) | 0/127 (0) | 3/126 (2.38) |
LSA | MCT | HSA | OSA | At Least One | |
Male < 6 months | 4/30 (13.33) | 2/30 (6.67) | 0/31 (0) | 0/30 (0) | 6/28 (21.43) † |
Male 6 – 11 months | 5/56 (8.93) | 4/56 (7.14) | 0/57 (0) | 0/61 (0) | 9/52 (17.31)*† |
Male 1 year | 5/39 (12.82) | 7/37 (18.92) | 1/39 (2.56) | 0/39 (0) | 12/38 (31.58) |
Male 2 – 8 years | 1/61 (1.64) | 3/54 (5.56) | 2/63 (3.17) | 0/65 (0) | 5/51 (9.8) |
Male Intact | 9/210 (4.29) | 26/224 (11.61) | 2/214 (0.93) | 1/218 (0.46) | 37/213 (17.37) |
Female < 6 months | 1/42 (2.38) | 6/48 (12.5) | 0/47 (0) | 0/50 (0) | 7/43 (16.28) |
Female 6 – 11 months | 3/68 (4.41) | 5/68 (7.35) | 1/67 (1.49) | 0/70 (0) | 9/64 (14.06) |
Female 1 year | 3/27 (11.11) | 2/27 (7.41) | 0/29 (0) | 0/28 (0) | 5/25 (20) |
Female 2 – 8 years | 1/57 (1.75) | 3/52 (5.77) | 0/57 (0) | 0/59 (0) | 4/46 (8.7) |
Female Intact | 3/126 (2.38) | 11/132 (8.33) | 0/125 (0) | 0/128 (0) | 14/129 (10.85) |
UI was reported in 1-2% of the spayed females.
Summary: The Best Boxer Spay & Neuter Times
The authors state that Boxers of both sexes should not be desexed until 2 years of age due to the high rate of cancers. However, a look at the data shows that females do not have an increased risk after desexing, and that males desexed at 6-11 months share the same risk as intact males.
Recommendation: between 6 and 12 months for males and one year for females.
This allows for the general trend of later times with higher body weights. It is later with females as they will come into season at 7-9 months, and we want this to settle down completely before surgery.
This is so far the only science we have for the best desexing age in Boxers. Your vet, breeder or online group may have a different opinion based on their experience or personal beliefs. It’s perfectly reasonable to take their advice into consideration as well.
The decision may also be based on other factors such as:
- local neutering legislation
- risk of male dog aggression to children
- risk of pregnancy or reluctance to manage a female in heat
- health problems associated with intact dogs
Problems With This Study
In the original paper, the authors appear to make some recommendations based on very limited evidence. I have published the original study data so you can see the actual numbers involved and decide for yourself.
The authors also do not mention the well-known increase in lifespan associated with desexing male and female dogs, which tends to counteract most concerns about specific cancers. The following comment in the paper is a clue that it might also have been true for this population:
Across all breeds the mean age of last entry in the record for neutered males was 5.5 years (range 3.71–6.54), for neutered females 5.7 years (range 4.21–6.97), for intact males 4.9 (range 4.15–7.11), and intact females 4.7 (range 3.41–6.32)
The study tries to also look at the rates of mammary cancer & pyometra in females, but cannot give an accurate assessment for two reasons:
- the mean ages listed above are far too young to pick up most cases
- pyometra and mammary cancer are rarely referred to university hospitals
Regardless of any concerns, the authors are to be applauded to bringing into focus one of the most common questions from dog owners. For Boxers at least, they’ve made the decision a lot easier.
Related: Best Desexing Age For 35 Breeds | Desexing Choices For Dogs | Costs Of Desexing
Have something to add? Comments (if open) will appear within 24 hours.
By Andrew Spanner BVSc(Hons) MVetStud, a vet in Adelaide, Australia. Meet his team here.
It dosen’t seem like that much difference in risk for Boxers who have been de sexed and not as far as cancer goes rought 21% get it either way?
Hi John. Thanks for reading the article closely – it’s why I added the data. Just to say that there is an increased risk doesn’t cover the nuances such as just how much of an increased risk there is. If you look through all of the similar pages, you’ll see that in most cases, this is true. It means that, although the neutering age recommendations we make fit the best available evidence, they should not be seen as hard and fast rules and should be adjusted in light of other environmental and health factors as well.
Should females still be desexed at 1 years old if they haven’t had their first heat yet?
Hi Hannah. In these cases, we feel that the first heat was clinically silent, but nonetheless happened. Therefore, our recommendation remains the same.
Thanks for sharing these findings! Boxer male–6 to 11 months neuter, now with a lot less ambivalence about it!
Thank you for this clear information. We have a female boxer and were confused by all the studies and recommendations.